Reactome | ERBB2 D769H [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

ERBB2 D769H [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9646616] Orlic-Milacic, Marija, 2019-05-27
crossReference	[DatabaseIdentifier:12021321] Mondo:0003812 [DatabaseIdentifier:9646614] COSMIC:COSV54062425 [DatabaseIdentifier:9646613] COSMIC:COSM4775196
dbId	9646617
disease	[Disease:1500689] cancer [Disease:1500576] breast cancer [Disease:9631134] cervical squamous cell carcinoma [Disease:1500687] stomach cancer [Disease:2317371] ovarian endometrioid neoplasm [Disease:1493885] bladder carcinoma
displayName	ERBB2 D769H [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9646615] L-aspartic acid 769 replaced with L-histidine
inDisease	true
literatureReference	[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
maxDepth	1
memberOf	[CandidateSet:R-HSA-9649439] ERBB2 KD mutants (lapatinib) [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9649468] ERBB2 KD mutants (trastuzumab) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9649436] ERBB2 KD mutants (neratinib) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9646481] ERBB2 KD mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9647029] Orlic-Milacic, Marija, 2019-05-29
name	ERBB2 D769H HER2 D769H ERBB2 Asp769His HER2 Asp769His
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9646617
startCoordinate	23

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