Reactome | HSPA8:substrate binds late endosomal phospholipids

Schema > Reaction > Entries

authored	[InstanceEdit:9637871] Varusai, Thawfeek, 2019-02-21
category	binding
compartment	[Compartment:70101] cytosol [Compartment:172574] late endosome membrane
created	[InstanceEdit:9631064] Varusai, Thawfeek, 2018-12-04
dbId	9631068
displayName	HSPA8:substrate binds late endosomal phospholipids
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
eventOf	[Pathway:R-HSA-9615710] Late endosomal microautophagy - Homo sapiens
followingEvent	[Reaction:R-HSA-9631065] Substrate translocates into late endosomal lumen - Homo sapiens
inferredFrom	[Reaction:R-MMU-9631076] Hspa8:substrate binds late endosomal phospholipids - Mus musculus
input	[Complex:R-HSA-9615717] HSPA8 bound autophagic substrates [cytosol] [SimpleEntity:R-ALL-9631069] PL [late endosome membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9631078] Microautophagy of cytosolic proteins by late endosomes
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HSPA8:substrate binds late endosomal phospholipids
output	[Complex:R-HSA-9631070] PL:HSPA8:Autophagy substrate [late endosome membrane]
precedingEvent	[Reaction:R-HSA-9615721] HSPA8 binds substrate - Homo sapiens
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9631068
summation	[Summation:9631074] Microautophagy (MI) can target KFERQ motif containing protei...

(hasEvent)	[Pathway:R-HSA-9615710] Late endosomal microautophagy
(precedingEvent)	[Reaction:R-HSA-9631065] Substrate translocates into late endosomal lumen
(inferredTo)	[Reaction:R-MMU-9631076] Hspa8:substrate binds late endosomal phospholipids

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