Reactome | Diseases of Cellular Senescence

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Diseases of Cellular Senescence Show undefined attributes

authored	[InstanceEdit:9632937] Orlic-Milacic, Marija, 2018-12-24
created	[InstanceEdit:9630746] Orlic-Milacic, Marija, 2018-12-03
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9630747
disease	[Disease:1500689] cancer
displayName	Diseases of Cellular Senescence
doi	10.3180/R-HSA-9630747.1
edited	[InstanceEdit:9645275] Orlic-Milacic, Marija, 2019-05-07
eventOf	[Pathway:R-HSA-9675132] Diseases of cellular response to stress - Homo sapiens
figure	[Figure:9830295] /figures/ehld/R-HSA-9630747.svg
hasDiagram	true
hasEHLD	true
hasEvent	[Pathway:R-HSA-9630750] Evasion of Oncogene Induced Senescence Due to p16INK4A Defects - Homo sapiens [Pathway:R-HSA-9646303] Evasion of Oncogene Induced Senescence Due to p14ARF Defects - Homo sapiens [Pathway:R-HSA-9632693] Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects - Homo sapiens [Pathway:R-HSA-9646304] Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2023-06-07
literatureReference	[LiteratureReference:9633970] Cellular senescence in aging and age-related disease: from mechanisms to therapy [LiteratureReference:9633975] Senescence in Health and Disease [LiteratureReference:9633902] Forging a signature of in vivo senescence
maxDepth	4
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Diseases of Cellular Senescence
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9645278] Bennett, Dorothy C, 2019-04-23 [InstanceEdit:9649238] Nathan, Vaishnavi, 2019-06-03 [InstanceEdit:9649237] Hayward, Nicholas K, 2019-06-03
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9630747
summation	[Summation:9633972] Cellular senescence plays an important role in normal aging,...
updateTrackers	[UpdateTracker:9835748] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v85:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777573] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v70:[addHasEvent, updateContainedPathway] [UpdateTracker:9846615] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v84:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9835748] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v85:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777573] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v70:[addHasEvent, updateContainedPathway]
[UpdateTracker:9846615] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v84:[addLiteratureReference, modifyText]

(hasEvent)

[Pathway:R-HSA-9675132] Diseases of cellular response to stress