Reactome | NEIL3 recognizes and binds to 5-guanidinohydantoin

Schema > Reaction > Entries

authored	[InstanceEdit:9634075] Orlic-Milacic, Marija, 2019-01-04
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9629371] Orlic-Milacic, Marija, 2018-11-20
dbId	9629358
displayName	NEIL3 recognizes and binds to 5-guanidinohydantoin
edited	[InstanceEdit:9636025] Orlic-Milacic, Marija, 2019-02-11
eventOf	[Pathway:R-HSA-110330] Recognition and association of DNA glycosylase with site containing an affected purine - Homo sapiens
followingEvent	[Reaction:R-HSA-9629470] NEIL3 cleaves 5-guanidinohydantoin - Homo sapiens
input	[DefinedSet:R-HSA-9629546] Gh-DNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9629184] NEIL3 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9629357] Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NEIL3 recognizes and binds to 5-guanidinohydantoin
output	[Complex:R-HSA-9629386] NEIL3:Gh-DNA [nucleoplasm]
releaseDate	2019-03-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9635970] Zhou, Jia, 2019-02-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9629358
summation	[Summation:9629387] NEIL3 recognizes and binds to oxidatively damaged guanine ba...

(hasEvent)	[Pathway:R-HSA-110330] Recognition and association of DNA glycosylase with site containing an affected purine
(precedingEvent)	[Reaction:R-HSA-9629470] NEIL3 cleaves 5-guanidinohydantoin

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