Reactome | PINK1 gene expression is stimulated by FOXO1,FOXO3

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018-10-11
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9621288] Orlic-Milacic, Marija, 2018-09-26
dbId	9621289
displayName	PINK1 gene expression is stimulated by FOXO1,FOXO3
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
eventOf	[Pathway:R-HSA-9614657] FOXO-mediated transcription of cell death genes - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9621286] Pink1 gene expression is stimulated by Foxo1 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9621276] PINK1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PINK1 gene expression is stimulated by FOXO1,FOXO3
output	[EntityWithAccessionedSequence:R-HSA-5205637] PINK1 [cytosol]
precedingEvent	[Reaction:R-HSA-9621270] FOXO1,FOXO3 bind PINK1 gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9621290] Positive gene expression regulation by 'FOXO1,FOXO3:PINK1 gene [nucleoplasm]'
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9625979] Donlon, Timothy, 2018-10-17 [InstanceEdit:9626974] Bertaggia, Enrico, 2018-10-26
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9621289
summation	[Summation:9621283] FOXO1 (Sengupta et al. 2011) and FOXO3 (Mei et al. 2009, Sen...

(hasEvent)	[Pathway:R-HSA-9614657] FOXO-mediated transcription of cell death genes
(inferredTo)	[BlackBoxEvent:R-MMU-9621286] Pink1 gene expression is stimulated by Foxo1

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