PINK1 gene expression is stimulated by FOXO1,FOXO3

Stable Identifier
R-HSA-9621289
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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PINK1 gene expression is stimulated by FOXO1,FOXO3
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FOXO1 (Sengupta et al. 2011) and FOXO3 (Mei et al. 2009, Sengupta et al. 2011) stimulate PINK1 gene transcription in both human (Mei et al. 2009) and mouse cells. FOXO3-mediated induction of PINK1 plays an important role in the survival of lymphocytes (Mei et al. 2009).

Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
FOXO1,FOXO3:PINK1 gene [nucleoplasm] (Homo sapiens)
Active Unit
FOXO1,FOXO3 [nucleoplasm]
Inferred From
Pink1 gene expression is stimulated by Foxo1 (Mus musculus)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-09-26)
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