Reactome | Long-term potentiation

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Long-term potentiation Show undefined attributes

authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
created	[InstanceEdit:9620245] Orlic-Milacic, Marija, 2018-09-21
crossReference	[DatabaseIdentifier:12819497] BioModels Database:BIOMD0000000467 [DatabaseIdentifier:12819463] BioModels Database:BIOMD0000000088 [DatabaseIdentifier:12819511] BioModels Database:BIOMD0000000468
dbId	9620244
displayName	Long-term potentiation
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-438064] Post NMDA receptor activation events - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-9618785] Calmodulin binds neurogranin - Homo sapiens [Reaction:R-HSA-9618811] Calcium binds calmodulin at the synapse - Homo sapiens [Reaction:R-HSA-442725] CaMKII binds activated calmodulin - Homo sapiens [Reaction:R-HSA-9617583] CaMKII autophosphorylates - Homo sapiens [Reaction:R-HSA-445367] CaMKII binds activated NMDA receptor - Homo sapiens [Reaction:R-HSA-9618750] CaMKII phosphorylates AMPA receptor - Homo sapiens [Reaction:R-HSA-9612085] SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9620239] Mechanisms of CaMKII action in long-term potentiation [LiteratureReference:9627673] NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD)
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Long-term potentiation
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9620244
summation	[Summation:9620249] In long-term potentiation (LTP), involved in learning and me...

Referrals

(hasEvent)

[Pathway:R-HSA-438064] Post NMDA receptor activation events