Reactome | CaMKK binds activated calmodulin in the cytosol

Schema > Reaction > Entries

authored	[InstanceEdit:445353] Mahajan, SS, 2009-10-29
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9619217] Orlic-Milacic, Marija, 2018-09-14
dbId	9619214
displayName	CaMKK binds activated calmodulin in the cytosol
edited	[InstanceEdit:422554] Gillespie, ME, 2009-06-02 00:56:21 [InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-9619229] Activation of RAC1 downstream of NMDARs - Homo sapiens
followingEvent	[Reaction:R-HSA-9619355] CaMKK autophosphorylates in the cytosol - Homo sapiens
inferredFrom	[Reaction:R-NUL-9619243] Camkk1 binds activated calmodulin in the cytosol - Homo sapiens [Reaction:R-NUL-9619239] Camkk2 binds activated calmodulin in the cytosol - Homo sapiens
input	[Complex:R-HSA-74294] CALM1:4xCa2+ [cytosol] [DefinedSet:R-HSA-9619227] CaMKK [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CaMKK binds activated calmodulin in the cytosol
output	[Complex:R-HSA-9619230] CaMKK:CALM1:4xCa2+ [cytosol]
releaseDate	2009-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:446792] Tukey, D, 2009-11-17 [InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9619214
summation	[Summation:9619220] Two isoforms of CaMKK, CAMKK1 (CaMKK alpha) and CAMKK2 (CaMK...

(hasEvent)	[Pathway:R-HSA-9619229] Activation of RAC1 downstream of NMDARs
(precedingEvent)	[Reaction:R-HSA-9619355] CaMKK autophosphorylates in the cytosol
(inferredTo)	[Reaction:R-NUL-9619243] Camkk1 binds activated calmodulin in the cytosol [Reaction:R-NUL-9619239] Camkk2 binds activated calmodulin in the cytosol

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