Reactome | AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex

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AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex Show undefined attributes

authored	[InstanceEdit:9667932] Gerace, Larry, 2019-11-07
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9615900] Orlic-Milacic, Marija, 2018-08-09
dbId	9615901
displayName	AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex
edited	[InstanceEdit:9668537] Orlic-Milacic, Marija, 2019-11-26
eventOf	[Pathway:R-HSA-9615933] Postmitotic nuclear pore complex (NPC) reformation - Homo sapiens
followingEvent	[Reaction:R-HSA-9618378] POM121 binds the Nup107-Nup160 complex - Homo sapiens
input	16 × [EntityWithAccessionedSequence:R-HSA-376244] AHCTF1 [cytosol] [DefinedSet:R-ALL-2537690] Chromatin [chromosome] 32 × [Complex:R-HSA-377883] Nup107-160 complex [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9615906] MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly [LiteratureReference:9615916] ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex
negativePrecedingEvent	[NegativePrecedingEvent:9764066] Futile Cycle: RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160
orthologousEvent	[Reaction:R-BTA-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Bos taurus [Reaction:R-CEL-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Caenorhabditis elegans [Reaction:R-DME-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Drosophila melanogaster [Reaction:R-GGA-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Gallus gallus [Reaction:R-XTR-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Xenopus tropicalis [Reaction:R-DRE-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Danio rerio [Reaction:R-SSC-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Sus scrofa [Reaction:R-CFA-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Canis familiaris [Reaction:R-RNO-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Rattus norvegicus [Reaction:R-MMU-9615901] AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex - Mus musculus
output	[Complex:R-HSA-9615902] Nup107-160 complex:AHCTF1:Chromatin [cytosol]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9615901
summation	[Summation:9615915] Based on studies in human and Xenopus model systems (Rasala ...

Referrals

(hasEvent)	[Pathway:R-HSA-9615933] Postmitotic nuclear pore complex (NPC) reformation
(precedingEvent)	[Reaction:R-HSA-9618378] POM121 binds the Nup107-Nup160 complex