Reactome | PTEN mRNA translation is inhibited by miR-137

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9615665] Orlic-Milacic, Marija, 2018-08-07
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9615567] Orlic-Milacic, Marija, 2018-08-07
dbId	9615571
displayName	PTEN mRNA translation is inhibited by miR-137
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
eventOf	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2318746] PTEN mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9615568] Inhibition of the Schizophrenia-Associated MicroRNA miR-137 Disrupts Nrg1? Neurodevelopmental Signal Transduction [LiteratureReference:9615505] Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PTEN mRNA translation is inhibited by miR-137
output	[EntityWithAccessionedSequence:R-HSA-199420] PTEN [cytosol]
precedingEvent	[Reaction:R-HSA-9615570] miR-137 binds PTEN mRNA - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:9615789] Negative gene expression regulation by 'PTEN mRNA:miR-137 RISC [cytosol]'
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07 [InstanceEdit:9608114] Christodoulou, John, 2018-08-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9615571
summation	[Summation:9615793] Based on studies in both human and mouse model systems, tran...

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