Reactome | MECP2 and SOX2 bind MIR137 gene

Schema > Reaction > Entries

authored	[InstanceEdit:9615665] Orlic-Milacic, Marija, 2018-08-07
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9615535] Orlic-Milacic, Marija, 2018-08-07
dbId	9615536
displayName	MECP2 and SOX2 bind MIR137 gene
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
eventOf	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9615554] MIR137 gene expression is inhibited by MECP2 and SOX2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9615549] Mecp2 and Sox2 bind Mir137 gene - Mus musculus
input	[CandidateSet:R-HSA-9005549] MECP2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9615528] MIR137 gene [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-452271] SOX2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MECP2 and SOX2 bind MIR137 gene
output	[Complex:R-HSA-9615538] MECP2:SOX2:MIR137 gene [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-9021183] MECP2 mRNA translation is inhibited by miR-132 - Homo sapiens
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07 [InstanceEdit:9608114] Christodoulou, John, 2018-08-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9615536
summation	[Summation:9615541] Based on studies in mouse neurons, MECP2 and SOX2 simultaneo...

(hasEvent)	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2
(precedingEvent)	[BlackBoxEvent:R-HSA-9615554] MIR137 gene expression is inhibited by MECP2 and SOX2
(inferredTo)	[Reaction:R-MMU-9615549] Mecp2 and Sox2 bind Mir137 gene

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