Reactome | FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4)

Schema > BlackBoxEvent > Entries

FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4) Show undefined attributes

authored	[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018-10-11
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:9614670] Orlic-Milacic, Marija, 2018-07-27
dbId	9614669
displayName	FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4)
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
eventOf	[Pathway:R-HSA-9614657] FOXO-mediated transcription of cell death genes - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6797248] FASLG gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9614547] Inhibition of phosphorylation of a forkhead transcription factor sensitizes human ovarian cancer cells to cisplatin [LiteratureReference:199277] Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor [LiteratureReference:9614683] Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells [LiteratureReference:9614691] miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4 [LiteratureReference:9614698] microRNA-150 promotes cervical cancer cell growth and survival by targeting FOXO4
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4)
output	[EntityWithAccessionedSequence:R-HSA-66212] FASLG(1-281) [extracellular region]
precedingEvent	[Reaction:R-HSA-9614662] FOXO1,FOXO3,(FOXO4) bind FASLG gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9614674] Positive gene expression regulation by 'FOXO1,FOXO3,(FOXO4):FASLG gene [nucleoplasm]'
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9625979] Donlon, Timothy, 2018-10-17 [InstanceEdit:9626974] Bertaggia, Enrico, 2018-10-26
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9614669
summation	[Summation:9614676] Binding of FOXO1 (Ciechomska et al. 2003) or FOXO3 (Brunet e...

Referrals

(hasEvent)

[Pathway:R-HSA-9614657] FOXO-mediated transcription of cell death genes

Cite Us!