Reactome | BRAF dimer complex [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-170965] (Frs2)Rap1-GTP binds to and activates B-Raf - Homo sapiens
created	[InstanceEdit:9610126] Rothfels, Karen, 2018-06-05
dbId	9610125
displayName	BRAF dimer complex [cytosol]
hasComponent	2 × [Complex:R-HSA-190075] B-Raf complex [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-9610125] BRAF dimer complex [cytosol] - Mus musculus [Complex:R-RNO-9610125] BRAF dimer complex [cytosol] - Rattus norvegicus [Complex:R-BTA-9610125] BRAF dimer complex [cytosol] - Bos taurus [Complex:R-SSC-9610125] BRAF dimer complex [cytosol] - Sus scrofa [Complex:R-GGA-9610125] BRAF dimer complex [cytosol] - Gallus gallus [Complex:R-DME-9610125] BRAF dimer complex [cytosol] - Drosophila melanogaster [Complex:R-CEL-9610125] BRAF dimer complex [cytosol] - Caenorhabditis elegans
isChimeric	false
name	BRAF dimer complex
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9610125

(input)	[Reaction:R-HSA-170965] (Frs2)Rap1-GTP binds to and activates B-Raf
(hasComponent)	[Complex:R-HSA-190082] RAP1:GTP:B-Raf complex [endosome membrane]
(activeUnit)	[CatalystActivity:9610159] protein serine/threonine kinase activity of RAP1:GTP:B-Raf complex [endosome membrane] [CatalystActivity:9610155] protein serine/threonine kinase activity of RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane]