Reactome | RAP1:GTP:B-Raf complex [endosome membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9610159] protein serine/threonine kinase activity of RAP1:GTP:B-Raf complex [endosome membrane]
compartment	[Compartment:74700] endosome membrane
consumedByEvent	[Reaction:R-HSA-9610163] BRAF autophosphorylates downstream of RAP1 and NGF - Homo sapiens
created	[InstanceEdit:190076] Jassal, B, 2006-12-14 13:53:55
dbId	190082
displayName	RAP1:GTP:B-Raf complex [endosome membrane]
hasComponent	[Complex:R-HSA-9610125] BRAF dimer complex [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol] [EntityWithAccessionedSequence:R-HSA-190053] RAP1A [endosome membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Mus musculus [Complex:R-RNO-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Rattus norvegicus [Complex:R-BTA-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Bos taurus [Complex:R-SSC-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Sus scrofa [Complex:R-GGA-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Gallus gallus [Complex:R-DME-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Drosophila melanogaster [Complex:R-CEL-190082] RAP1:GTP:B-Raf complex [endosome membrane] - Caenorhabditis elegans
modified	[InstanceEdit:9610142] Rothfels, Karen, 2018-06-05
name	RAP1:GTP:B-Raf complex
producedByEvent	[Reaction:R-HSA-170965] (Frs2)Rap1-GTP binds to and activates B-Raf - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-190082

(output)	[Reaction:R-HSA-170965] (Frs2)Rap1-GTP binds to and activates B-Raf
(input)	[Reaction:R-HSA-9610163] BRAF autophosphorylates downstream of RAP1 and NGF
(physicalEntity)	[CatalystActivity:9610159] protein serine/threonine kinase activity of RAP1:GTP:B-Raf complex [endosome membrane]