Reactome | HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG)

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HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG) Show undefined attributes

authored	[InstanceEdit:9609684] Gillespie, Marc E, 2018-05-29
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9609691] Gillespie, Marc E, 2018-05-29
crossReference	[DatabaseIdentifier:12020762] Mondo:0005108
dbId	9609689
disease	[Disease:3134794] viral infectious disease
displayName	HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG)
eventOf	[Pathway:R-HSA-9609690] HCMV Early Events - Homo sapiens
followingEvent	[Reaction:R-HSA-9611158] Fusion of HCMV Envelope with Plasma Membrane - Homo sapiens
input	[DefinedSet:R-HSA-9610864] HCMV Host Cell Receptors [plasma membrane] [Complex:R-HCY-9610868] HCMV Mature Virion without pentameric complex [extracellular region] [SimpleEntity:R-ALL-1678620] HSPG [plasma membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9610866] Heparan sulfate proteoglycans [Book:9609668] Fields Virology 1451105630 Knipe, David Mahan Chapter 62 - Cytomegaloviruses [LiteratureReference:9652658] Deletion of gpUL132, a structural component of human cytomegalovirus, results in impaired virus replication in fibroblasts
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG)
output	[Complex:R-HSA-9610977] Enveloped HCMV Virion without Pentameric Complex Bound to Entry Mediator [extracellular region]
relatedSpecies	[Species:2671791] Human cytomegalovirus
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9663908] Caposio, Patrizia, Streblow, Daniel N, 2019-10-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9609689
summation	[Summation:9610869] Viral attachment and penetration of Human Cytomegalovirus (H...

Referrals

(hasEvent)	[Pathway:R-HSA-9609690] HCMV Early Events
(precedingEvent)	[Reaction:R-HSA-9611158] Fusion of HCMV Envelope with Plasma Membrane

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