Reactome | MUTYH binding LOF mutants [nucleoplasm]

Schema > DefinedSet > Entries

MUTYH binding LOF mutants [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[FailedReaction:R-HSA-9608288] Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine - Homo sapiens
created	[InstanceEdit:9608301] Orlic-Milacic, Marija, 2018-05-11
crossReference	[DatabaseIdentifier:12020963] Mondo:0021055
dbId	9608300
disease	[Disease:9605309] familial adenomatous polyposis [Disease:4791250] colorectal cancer
displayName	MUTYH binding LOF mutants [nucleoplasm]
hasMember	[EntityWithAccessionedSequence:R-HSA-9605328] MUTYH-3 Y165C [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9605325] MUTYH-3 G382D [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606261] MUTYH-3 R227W [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606264] MUTYH-3 V232F [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606290] MUTYH-3 R231L [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606297] MUTYH-3 R231H [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606359] MUTYH-3 R260Q [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606354] MUTYH-3 P281L [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606455] MUTYH-3 A368fs26 [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606420] MUTYH-3 E466 [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606415] MUTYH-3 Q377* [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9606418] MUTYH-3 Y90* [nucleoplasm] - Homo sapiens
inDisease	true
maxDepth	2
name	MUTYH binding LOF mutants
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9608300

Referrals

(input)	[FailedReaction:R-HSA-9608288] Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine
(diseaseEntity)	[EntityFunctionalStatus:9608299] loss_of_function of MUTYH binding LOF mutants [nucleoplasm]

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