Reactome | CD19 is phosphorylated

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9606896] May, Bruce, 2018-04-22
category	uncertain
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9606882] May, Bruce, 2018-04-26
dbId	9606883
deleted	[Deleted:9613688] Deletion of instance: 983704
displayName	CD19 is phosphorylated
edited	[InstanceEdit:9606896] May, Bruce, 2018-04-22
eventOf	[Pathway:R-HSA-983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers - Homo sapiens
followingEvent	[Reaction:R-HSA-9606887] p-CD19:VAV binds PI3K and GRB2 - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9607042] Cd19 is phosphorylated - Mus musculus
input	6 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-2076225] CD19:VAV1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:2076262] Tyrosine phosphorylation of CD19 in pre-B and mature B cells
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CD19 is phosphorylated
output	6 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-9606889] p-CD19:VAV1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-983696] The Immunoglobulin of the BCR binds antigen - Homo sapiens
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9613695] Wienands, J, 2018-07-18
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9606883
summation	[Summation:9607056] In response to BCR activation, CD19 in a stable complex with...

(replacementInstances)	[Deleted:9613688] Deletion of instance: 983704
(hasEvent)	[Pathway:R-HSA-983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
(precedingEvent)	[Reaction:R-HSA-9606887] p-CD19:VAV binds PI3K and GRB2
(inferredTo)	[BlackBoxEvent:R-MMU-9607042] Cd19 is phosphorylated

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