Reactome | Active FLT3 binds FYN

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Active FLT3 binds FYN Show undefined attributes

authored	[InstanceEdit:9634693] Varusai, Thawfeek, 2019-01-14
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9605256] Varusai, Thawfeek, 2018-04-09
dbId	9605259
displayName	Active FLT3 binds FYN
edited	[InstanceEdit:9634693] Varusai, Thawfeek, 2019-01-14
eventOf	[Pathway:R-HSA-9706374] FLT3 signaling through SRC family kinases - Homo sapiens
inferredFrom	[Reaction:R-MMU-9605258] Active Flt3 binds Fyn - Mus musculus
input	[Complex:R-HSA-9604751] Active FLT3 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-200917] FYN [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9605263] FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia [LiteratureReference:6786760] Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Active FLT3 binds FYN
output	[Complex:R-HSA-9605257] Active FLT3:FYN [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9604767] FLT3LG dimer:FLT3 dimer autophosphorylates - Homo sapiens
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9645124] Traer, Elie, 2019-05-03 [InstanceEdit:9646275] Joshi, Sunil, 2019-05-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9605259
summation	[Summation:9605261] Feline McDonough Sarcoma-like tyrosine kinase (FLT3) is a me...

Referrals

(hasEvent)	[Pathway:R-HSA-9706374] FLT3 signaling through SRC family kinases
(inferredTo)	[Reaction:R-MMU-9605258] Active Flt3 binds Fyn

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