Reactome | Expression of FASN regulated by NR1H2 or NR1H3

Schema > BlackBoxEvent > Entries

Expression of FASN regulated by NR1H2 or NR1H3 Show undefined attributes

authored	[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9605053] Shamovsky, Veronica, 2018-04-06
dbId	9605063
displayName	Expression of FASN regulated by NR1H2 or NR1H3
edited	[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
eventOf	[Pathway:R-HSA-9029558] NR1H2 & NR1H3 regulate gene expression linked to lipogenesis - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2393979] FASN gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9024431] Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors [LiteratureReference:9028536] The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of FASN regulated by NR1H2 or NR1H3
output	[EntityWithAccessionedSequence:R-HSA-199233] FASN [cytosol]
precedingEvent	[Reaction:R-HSA-9028533] NR1H2,3, NRIP1 bind the FASN gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-9035453] Positive gene expression regulation by 'NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:FASN gene [nucleoplasm]'
regulationReference	[RegulationReference:9641398] Positive gene expression regulation by 'NRIP1:NR1H2,3:RXR:NR1H2,3 ligand:FASN gene [nucleoplasm]' The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor
releaseDate	2019-09-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29 [InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9605063
summation	[Summation:9605064] The fatty acid synthase (FAS or FASN) gene is transcribed to...

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[Pathway:R-HSA-9029558] NR1H2 & NR1H3 regulate gene expression linked to lipogenesis

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