Reactome | JAG1 binds NOTCH4

Schema > Reaction > Entries

JAG1 binds NOTCH4 Show undefined attributes

authored	[InstanceEdit:157021] Jassal, B, 2004-12-15 13:08:03 [InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9604246] Orlic-Milacic, Marija, 2018-04-02
dbId	9604247
deleted	[Deleted:9608084] Deletion of instance: 157633
displayName	JAG1 binds NOTCH4
edited	[InstanceEdit:9608067] Orlic-Milacic, Marija, 2018-05-09
entityOnOtherCell	[EntityWithAccessionedSequence:R-HSA-157098] JAG1 [plasma membrane] - Homo sapiens
eventOf	[Pathway:R-HSA-9013700] NOTCH4 Activation and Transmission of Signal to the Nucleus - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9604264] ADAM10 cleaves NOTCH4 - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:24616] positive regulation of Notch signaling pathway
inferredFrom	[Reaction:R-MMU-9604251] Jag1 binds Notch4 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-157098] JAG1 [plasma membrane] [Complex:R-HSA-157053] NOTCH4 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	JAG1 binds NOTCH4
output	[Complex:R-HSA-9604245] JAG1:NOTCH4 [plasma membrane]
releaseDate	2005-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:165114] Joutel, A, 2004-12-15 [InstanceEdit:9608066] Haw, Robin, 2018-05-01
revised	[InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9604247
summation	[Summation:9604257] JAG1 can activate NOTCH4 signaling, based on co-culture of J...

Referrals

(replacementInstances)	[Deleted:9608084] Deletion of instance: 157633
(hasEvent)	[Pathway:R-HSA-9013700] NOTCH4 Activation and Transmission of Signal to the Nucleus
(precedingEvent)	[BlackBoxEvent:R-HSA-9604264] ADAM10 cleaves NOTCH4
(inferredTo)	[Reaction:R-MMU-9604251] Jag1 binds Notch4

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