Reactome | Protein tyrosine phosphatases dephosphorylate NTRK3

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Protein tyrosine phosphatases dephosphorylate NTRK3 Show undefined attributes

authored	[InstanceEdit:9034018] Orlic-Milacic, Marija, 2018-01-02
catalystActivity	[CatalystActivity:9603722] protein tyrosine phosphatase activity of (PTPRO,PTPRS) [plasma membrane]
category	uncertain
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9603716] Orlic-Milacic, Marija, 2018-03-23
dbId	9603719
displayName	Protein tyrosine phosphatases dephosphorylate NTRK3
edited	[InstanceEdit:9608101] Orlic-Milacic, Marija, 2018-05-09
eventOf	[Pathway:R-HSA-9034015] Signaling by NTRK3 (TRKC) - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:171483] negative regulation of neurotrophin TRK receptor signaling pathway
inferredFrom	[BlackBoxEvent:R-NUL-9603754] PTPRS dephosphorylates Ntrk3 - Gallus gallus [BlackBoxEvent:R-NUL-9603766] PTPRO dephosphorylate NTRK3 - Gallus gallus
input	10 × [SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-HSA-9034727] NTF3:p-5Y-NTRK3 homodimer [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9865796] Orlic-Milacic, Marija, 2024-03-18
name	Protein tyrosine phosphatases dephosphorylate NTRK3
negativePrecedingEvent	[NegativePrecedingEvent:9865790] Futile Cycle: Activated PCLG1 dissociates from NTRK3
output	[Complex:R-HSA-9034025] NTF3:NTRK3 homodimer [plasma membrane] 10 × [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-HSA-9034714] NTRK3 dimers trans-autophosphorylate - Homo sapiens
releaseDate	2018-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608098] Tsoulfas, Pantelis, 2018-05-09
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9603719
summation	[Summation:9603728] Receptor protein tyrosine phosphatases PTPRO and PTPRS (PTPs...

Referrals

(hasEvent)	[Pathway:R-HSA-9034015] Signaling by NTRK3 (TRKC)
(precedingEvent)	[NegativePrecedingEvent:9865794] Negative relationship: Protein tyrosine phosphatases dephosphorylate NTRK3
(inferredTo)	[BlackBoxEvent:R-NUL-9603754] PTPRS dephosphorylates Ntrk3 [BlackBoxEvent:R-NUL-9603766] PTPRO dephosphorylate NTRK3

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