Reactome | Cyclisation of GTP to precursor Z

Schema > Reaction > Entries

Cyclisation of GTP to precursor Z Show undefined attributes

authored	[InstanceEdit:947516] Stephan, R, 2010-09-01
catalystActivity	[CatalystActivity:947552] S-adenosyl-L-methionine binding activity of holo-MOCS1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:947525] Jassal, B, 2010-09-08
dbId	947535
displayName	Cyclisation of GTP to precursor Z
edited	[InstanceEdit:947525] Jassal, B, 2010-09-08
eventOf	[Pathway:R-HSA-947581] Molybdenum cofactor biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-947541] Sulfhydrylation and ring cleavage of precursor Z - Homo sapiens
input	[SimpleEntity:R-ALL-71284] AdoMet [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:947510] Functionality of alternative splice forms of the first enzymes involved in human molybdenum cofactor biosynthesis [LiteratureReference:947497] Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Cyclisation of GTP to precursor Z
orthologousEvent	[Reaction:R-DDI-947535] Cyclisation of GTP to precursor Z - Dictyostelium discoideum [Reaction:R-CEL-947535] Cyclisation of GTP to precursor Z - Caenorhabditis elegans [Reaction:R-DME-947535] Cyclisation of GTP to precursor Z - Drosophila melanogaster [Reaction:R-GGA-947535] Cyclisation of GTP to precursor Z - Gallus gallus [Reaction:R-XTR-947535] Cyclisation of GTP to precursor Z - Xenopus tropicalis [Reaction:R-SSC-947535] Cyclisation of GTP to precursor Z - Sus scrofa [Reaction:R-BTA-947535] Cyclisation of GTP to precursor Z - Bos taurus [Reaction:R-CFA-947535] Cyclisation of GTP to precursor Z - Canis familiaris [Reaction:R-RNO-947535] Cyclisation of GTP to precursor Z - Rattus norvegicus [Reaction:R-MMU-947535] Cyclisation of GTP to precursor Z - Mus musculus
output	[SimpleEntity:R-ALL-947703] dADE [cytosol] [SimpleEntity:R-ALL-174390] L-Met [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol] [SimpleEntity:R-ALL-947537] Precursor Z [cytosol]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:994085] D'Eustachio, P, 2010-11-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-947535
summation	[Summation:947506] GTP cyclizes in a reaction involving radicals of S-adenosylm...

Referrals

(precedingEvent)	[Reaction:R-HSA-947541] Sulfhydrylation and ring cleavage of precursor Z
(hasEvent)	[Pathway:R-HSA-947581] Molybdenum cofactor biosynthesis