Reactome | IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]

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IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:166117] protein serine/threonine kinase activity of IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-937059] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex - Homo sapiens
created	[InstanceEdit:937009] Shamovsky, V, 2010-08-25
dbId	937028
displayName	IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]
hasComponent	4 × [EntityWithAccessionedSequence:R-HSA-937014] IRAK2 [plasma membrane] [Complex:R-HSA-937048] p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
literatureReference	[LiteratureReference:937049] Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
maxDepth	10
modified	[InstanceEdit:8959586] Weiser, JD
name	IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR
relatedSpecies	[Species:181384] Chlamydia trachomatis [Species:180800] Neisseria meningitidis serogroup B
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-937028
updateTrackers	[UpdateTracker:9874056] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v43:[updateContainedComponent] [UpdateTracker:9870354] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9891657] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v52:[updateContainedComponent] [UpdateTracker:9871940] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v41:[updateContainedComponent] [UpdateTracker:9895908] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v60:[removeSpecies, updateContainedComponent] [UpdateTracker:9870935] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v39:[updateContainedComponent] [UpdateTracker:9902054] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v76:[updateContainedComponent] [UpdateTracker:9892801] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v54:[updateContainedComponent] [UpdateTracker:9899568] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v66:[updateContainedComponent] [UpdateTracker:9873183] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9899705] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9895080] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v59:[updateContainedComponent] [UpdateTracker:9889409] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v49:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9874056] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v43:[updateContainedComponent] [UpdateTracker:9870354] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9891657] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v52:[updateContainedComponent] [UpdateTracker:9871940] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v41:[updateContainedComponent] [UpdateTracker:9895908] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v60:[removeSpecies, updateContainedComponent] [UpdateTracker:9870935] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v39:[updateContainedComponent] [UpdateTracker:9902054] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v76:[updateContainedComponent] [UpdateTracker:9892801] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v54:[updateContainedComponent] [UpdateTracker:9899568] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v66:[updateContainedComponent] [UpdateTracker:9873183] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9899705] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9895080] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v59:[updateContainedComponent] [UpdateTracker:9889409] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v49:[updateContainedComponent]
(input)	[Reaction:R-HSA-937059] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex
(physicalEntity)	[CatalystActivity:166117] protein serine/threonine kinase activity of IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]

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