Reactome | Neisseria meningitidis serogroup B

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Neisseria meningitidis serogroup B Show undefined attributes

abbreviation	NME
created	[InstanceEdit:180798] de Bono, B, 2006-06-06 09:45:37
crossReference	[DatabaseIdentifier:180799] NCBI_taxonomy:491
dbId	180800
displayName	Neisseria meningitidis serogroup B
modified	[InstanceEdit:9014479] Weiser, JD
name	Neisseria meningitidis serogroup B
schemaClass	Species
superTaxon	[Species:180808] Neisseria meningitidis
taxId	491

Referrals

(relatedSpecies)

[Pathway:R-HSA-5602498] MyD88 deficiency (TLR2/4)
[FailedReaction:R-HSA-5602606] Defective MyD88 does not bind MAL(TIRAP):TLR2/4
[FailedReaction:R-HSA-5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex
[Complex:R-HSA-9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane]
[Pathway:R-HSA-5603041] IRAK4 deficiency (TLR2/4)
[FailedReaction:R-HSA-5602672] Defective IRAK4 does not bind MyD88 within the TLR2/4 complex
[FailedReaction:R-HSA-5602353] Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4
[Pathway:R-HSA-168898] Toll-like Receptor Cascades
[Pathway:R-HSA-166016] Toll Like Receptor 4 (TLR4) Cascade
[Pathway:R-HSA-166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane
[Complex:R-HSA-2559462] TLR1:TLR2 ligand:CD14 [plasma membrane]
[Complex:R-HSA-181226] TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane]
[DefinedSet:R-HSA-181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane]
[Complex:R-HSA-2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane]
[Complex:R-HSA-937033] oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane]
[Complex:R-HSA-937048] p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane]
[Complex:R-HSA-166360] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-937053] TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-166080] IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-166281] pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-166118] p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane]
[Complex:R-HSA-166062] MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane]
[Complex:R-HSA-2201331] TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane]
[Complex:R-HSA-2559411] TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane]
[Reaction:R-HSA-2559468] TLR1/2 ligand binds to CD14
[Reaction:R-HSA-168951] TLR1:TLR2 is recruited to ligand:CD14
[Reaction:R-HSA-2201316] Activated TLR2/4 interacts with MAL (TIRAP)
[Reaction:R-HSA-2559414] Activated TLR2/4:TIRAP interacts with BTK
[Reaction:R-HSA-2201322] TIRAP is phosphorylated by BTK
[Reaction:R-HSA-166072] MyD88 forms a complex with TIRAP:activated TLR2/4
[Reaction:R-HSA-937079] MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88
[Reaction:R-HSA-166082] IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex
[Reaction:R-HSA-937022] IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP
[Reaction:R-HSA-166091] IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex
[Reaction:R-HSA-166119] First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal
[Reaction:R-HSA-166284] Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP
[Reaction:R-HSA-166286] Multiple IRAK1 autophosphorylation steps
[Reaction:R-HSA-166363] TRAF6 binds to hp- IRAK1
[Reaction:R-HSA-166362] Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex
[Complex:R-HSA-937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]
[Complex:R-HSA-937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Reaction:R-HSA-937059] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex
[Complex:R-HSA-2262774] TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
[Reaction:R-HSA-2262777] TRAF6 binds to p-IRAK2
[Reaction:R-HSA-2262775] Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex
[Pathway:R-HSA-168188] Toll Like Receptor TLR6:TLR2 Cascade
[Pathway:R-HSA-181438] Toll Like Receptor 2 (TLR2) Cascade
[Pathway:R-HSA-168179] Toll Like Receptor TLR1:TLR2 Cascade

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