Reactome | Y55/Y227-pSPRY2:CBL [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:934571] ubiquitin protein ligase activity of Y55/Y227-pSPRY2:CBL [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-934604] Phosphorylated SPRY2 is ubiquitinated by CBL - Homo sapiens
created	[InstanceEdit:934557] Williams, MG, 2010-08-17
dbId	934576
displayName	Y55/Y227-pSPRY2:CBL [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-112199] CBL [cytosol] [EntityWithAccessionedSequence:R-HSA-934555] p-Y55,Y227-SPRY2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Mus musculus [Complex:R-RNO-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Rattus norvegicus [Complex:R-CFA-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Canis familiaris [Complex:R-BTA-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Bos taurus [Complex:R-SSC-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Sus scrofa [Complex:R-DRE-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Danio rerio [Complex:R-GGA-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Gallus gallus [Complex:R-DME-934576] Y55/Y227-pSPRY2:CBL [plasma membrane] - Drosophila melanogaster
isChimeric	false
maxDepth	2
modified	[InstanceEdit:1584623] Rothfels, K, 2011-09-08
name	Y55/Y227-pSPRY2:CBL Y55/Y227-phospho Sprouty 2:CBL
producedByEvent	[Reaction:R-HSA-1295622] SPRY2 binds CBL - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-934576

(input)	[Reaction:R-HSA-934604] Phosphorylated SPRY2 is ubiquitinated by CBL
(physicalEntity)	[CatalystActivity:934571] ubiquitin protein ligase activity of Y55/Y227-pSPRY2:CBL [plasma membrane]
(output)	[Reaction:R-HSA-1295622] SPRY2 binds CBL

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