Reactome | PKA/PKG phosphorylate Rap1GAP2

Schema > Reaction > Entries

PKA/PKG phosphorylate Rap1GAP2 Show undefined attributes

authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:913994] protein serine/threonine kinase activity of PKA catalytic subunits, PKG type I [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:913995] Jupe, S, 2010-07-20
dbId	913996
displayName	PKA/PKG phosphorylate Rap1GAP2
edited	[InstanceEdit:939732] Jupe, S, 2010-09-01
eventOf	[Pathway:R-HSA-392517] Rap1 signalling - Homo sapiens
followingEvent	[Reaction:R-HSA-913993] 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-HSA-392491] RAP1GAP2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:430240] Rap1GAP2 is a new GTPase-activating protein of Rap1 expressed in human platelets
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	PKA/PKG phosphorylate Rap1GAP2
orthologousEvent	[Reaction:R-DDI-913996] PKA/PKG phosphorylate Rap1GAP2 - Dictyostelium discoideum [Reaction:R-CEL-913996] PKA/PKG phosphorylate Rap1GAP2 - Caenorhabditis elegans [Reaction:R-DME-913996] PKA/PKG phosphorylate Rap1GAP2 - Drosophila melanogaster [Reaction:R-GGA-913996] PKA/PKG phosphorylate Rap1GAP2 - Gallus gallus [Reaction:R-XTR-913996] PKA/PKG phosphorylate Rap1GAP2 - Xenopus tropicalis [Reaction:R-DRE-913996] PKA/PKG phosphorylate Rap1GAP2 - Danio rerio [Reaction:R-SSC-913996] PKA/PKG phosphorylate Rap1GAP2 - Sus scrofa [Reaction:R-BTA-913996] PKA/PKG phosphorylate Rap1GAP2 - Bos taurus [Reaction:R-CFA-913996] PKA/PKG phosphorylate Rap1GAP2 - Canis familiaris [Reaction:R-RNO-913996] PKA/PKG phosphorylate Rap1GAP2 - Rattus norvegicus [Reaction:R-MMU-913996] PKA/PKG phosphorylate Rap1GAP2 - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-HSA-913989] p-S7-RAP1GAP2 [cytosol]
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:939806] Heemskerk, JW, 2010-09-01
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-913996
summation	[Summation:939805] cGMP and cAMP dependent protein kinases (PKG and PKA respect...

Referrals

(precedingEvent)	[Reaction:R-HSA-913993] 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2
(hasEvent)	[Pathway:R-HSA-392517] Rap1 signalling