Reactome | PKA/PKG phosphorylate Rap1GAP2

Schema > Reaction > Entries

PKA/PKG phosphorylate Rap1GAP2 Show undefined attributes

catalystActivity	[CatalystActivity:10369698] protein serine/threonine kinase activity of PKA catalytic subunits, PKG type I [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10369700
displayName	PKA/PKG phosphorylate Rap1GAP2
eventOf	[Pathway:R-BTA-392517] Rap1 signalling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-913993] 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 - Bos taurus
inferredFrom	[Reaction:R-HSA-913996] PKA/PKG phosphorylate Rap1GAP2 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-BTA-392491] RAP1GAP2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PKA/PKG phosphorylate Rap1GAP2
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-BTA-913989] phospho-RAP1GAP2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-913996
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-392517] Rap1 signalling
(precedingEvent)	[Reaction:R-BTA-913993] 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2
(inferredTo)	[Reaction:R-HSA-913996] PKA/PKG phosphorylate Rap1GAP2

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