Reactome | p-Y1054,Y1055-TYK2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

p-Y1054,Y1055-TYK2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-997302] p-STAT2:STAT1:p-IFNAR1:p-TYK2 [plasma membrane] - Homo sapiens [Complex:R-HSA-909707] IFNAR1:p-TYK2 [plasma membrane] - Homo sapiens
created	[InstanceEdit:909678] Garapati, P V, 2010-07-07
dbId	909682
displayName	p-Y1054,Y1055-TYK2 [cytosol]
endCoordinate	1187
hasModifiedResidue	[ModifiedResidue:909679] O4'-phospho-L-tyrosine at 1055 [ModifiedResidue:909677] O4'-phospho-L-tyrosine at 1054
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-909682] phospho-p-Y1054,Y1055-TYK2 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-909682] phospho-p-Y1054,Y1055-TYK2 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-909682] phospho-TYK2 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-909682] phospho-p-Y1054,Y1055-TYK2 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-909682] phospho-p-Y1054,Y1055-TYK2 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-909682] phospho-p-Y1054,Y1055-TYK2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-GGA-909682] phospho-p-Y1054,Y1055-TYK2 [cytosol] - Gallus gallus
maxDepth	1
modified	[InstanceEdit:3322334] Wu, G, 2013-05-03
name	p-Y1054,Y1055-TYK2 p-TYK2 phospho-TYK2 phosphorylated TYK2
positivelyRegulates	[PositiveGeneExpressionRegulation:9850988] Positive gene expression regulation by 'p-Y1054,Y1055-TYK2 [cytosol]'
producedByEvent	[Reaction:R-HSA-9851114] NPM1-ALK-dependent TYK2 phosphorylation - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P29597] UniProt:P29597 TYK2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-909682
startCoordinate	1
updateTrackers	[UpdateTracker:9880286] Update Tracker - [EntityWithAccessionedSequence:909682] p-Y1054,Y1055-TYK2 [cytosol] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9880286] Update Tracker - [EntityWithAccessionedSequence:909682] p-Y1054,Y1055-TYK2 [cytosol] - v45:[addName]
(output)	[Reaction:R-HSA-9851114] NPM1-ALK-dependent TYK2 phosphorylation
(regulator)	[PositiveGeneExpressionRegulation:9850988] Positive gene expression regulation by 'p-Y1054,Y1055-TYK2 [cytosol]'
(hasComponent)	[Complex:R-HSA-997302] p-STAT2:STAT1:p-IFNAR1:p-TYK2 [plasma membrane] [Complex:R-HSA-912684] p-IFNAR1:p-TYK2:SOCS-1/SOCS-3 [plasma membrane] [Complex:R-HSA-909707] IFNAR1:p-TYK2 [plasma membrane] [Complex:R-HSA-909694] p-IFNAR1:p-TYK2 [plasma membrane] [Complex:R-HSA-909701] STAT2:p-IFNAR1:p-TYK2 [plasma membrane] [Complex:R-HSA-909712] p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane] [Complex:R-HSA-909709] p-STAT2:p-IFNAR1:p-TYK2 [plasma membrane]
(activeUnit)	[CatalystActivity:909723] protein tyrosine kinase activity of IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] [CatalystActivity:909731] protein tyrosine kinase activity of IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane]