Reactome | SRC,FYN phosphorylate NTRK2

Schema > Reaction > Entries

authored	[InstanceEdit:9034391] Orlic-Milacic, Marija, 2018-01-05
catalystActivity	[CatalystActivity:9037045] protein tyrosine kinase activity of MyrG-p-Y419-SRC,(MyrG-p-Y420-FYN-1) [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9037041] Orlic-Milacic, Marija, 2018-02-16
dbId	9037040
displayName	SRC,FYN phosphorylate NTRK2
edited	[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
eventOf	[Pathway:R-HSA-9032500] Activated NTRK2 signals through FYN - Homo sapiens
inferredFrom	[Reaction:R-RNO-9037056] Src phosphorylates Ntrk2 - Rattus norvegicus
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-HSA-6798236] NTRK2 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SRC,FYN phosphorylate NTRK2
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-HSA-9037044] p-Y706,Y707-NTRK2 [plasma membrane]
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9037707] Antila, Hanna, 2018-02-13 [InstanceEdit:9037710] Castr�n, Eero, 2018-02-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9037040
summation	[Summation:9037042] Activated SRC and, probably FYN, can phosphorylate NTRK2 (TR...

(hasEvent)	[Pathway:R-HSA-9032500] Activated NTRK2 signals through FYN
(inferredTo)	[Reaction:R-RNO-9037056] Src phosphorylates Ntrk2

Cite Us!