Reactome | Activated NTRK3 binds PLCG1

Schema > Reaction > Entries

authored	[InstanceEdit:9034018] Orlic-Milacic, Marija, 2018-01-02
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9034795] Orlic-Milacic, Marija, 2018-01-11
dbId	9034796
displayName	Activated NTRK3 binds PLCG1
edited	[InstanceEdit:9608101] Orlic-Milacic, Marija, 2018-05-09
eventOf	[Pathway:R-HSA-9034793] Activated NTRK3 signals through PLCG1 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9034814] NTRK3 phosphorylates PLCG1 - Homo sapiens
inferredFrom	[Reaction:R-NUL-9034794] Activated Ntrk3 binds Plcg1 - Homo sapiens
input	[Complex:R-HSA-9034727] NTF3:p-5Y-NTRK3 homodimer [plasma membrane] [EntityWithAccessionedSequence:R-HSA-167682] PLCG1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9865796] Orlic-Milacic, Marija, 2024-03-18
name	Activated NTRK3 binds PLCG1
negativePrecedingEvent	[NegativePrecedingEvent:9865789] Futile Cycle: Activated PCLG1 dissociates from NTRK3
output	[Complex:R-HSA-9034798] NTF3:p-5Y-NTRK3 homodimer:PLCG1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-9034714] NTRK3 dimers trans-autophosphorylate - Homo sapiens
releaseDate	2018-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608098] Tsoulfas, Pantelis, 2018-05-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9034796
summation	[Summation:9034797] Upon activation by NTF3 (NT-3), autophosphorylated NTRK3 (TR...

(hasEvent)	[Pathway:R-HSA-9034793] Activated NTRK3 signals through PLCG1
(precedingEvent)	[BlackBoxEvent:R-HSA-9034814] NTRK3 phosphorylates PLCG1
(inferredTo)	[Reaction:R-NUL-9034794] Activated Ntrk3 binds Plcg1

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