Reactome | Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA

Schema > Reaction > Entries

authored	[InstanceEdit:9027559] Jassal, Bijay, 2017-11-02
catalystActivity	[CatalystActivity:9027560] alcohol dehydrogenase (NADP+) activity of Dehydrogenase [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9027542] Jassal, Bijay, 2017-11-02
dbId	9027531
displayName	Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA
edited	[InstanceEdit:9027559] Jassal, Bijay, 2017-11-02
eventOf	[Pathway:R-HSA-9027604] Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9032315] oxo-DHAs translocate from cytosol to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-9027547] 13-HDHA [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9027533] Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA
output	[SimpleEntity:R-ALL-9027537] 13-oxo-DHA [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
precedingEvent	[Reaction:R-HSA-9027532] PTGS2 dimer oxidises DHA to 13-HDHA - Homo sapiens
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9027531
summation	[Summation:9027535] In activated macrophages, an unknown dehdyrogenase abstracts...

(precedingEvent)	[BlackBoxEvent:R-HSA-9032315] oxo-DHAs translocate from cytosol to extracellular region
(hasEvent)	[Pathway:R-HSA-9027604] Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives

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