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Schema
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Reaction
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Entries
DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)
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authored
[InstanceEdit:421433] May, B, 2009-05-18 21:31:59
catalystActivity
[CatalystActivity:400498] serine-type endopeptidase activity of DPP4(39-766) [extracellular region]
catalystActivityReference
[CatalystActivityReference:9644120] serine-type endopeptidase activity of DPP4(39-766) [extracellular region] Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
category
transition
compartment
[Compartment:984] extracellular region
created
[InstanceEdit:9023628] May, Bruce, 2017-09-28
dbId
9023626
deleted
[Deleted:9023668] Deletion of instance: 400513
displayName
DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)
edited
[InstanceEdit:435259] May, B, 2009-09-09
eventOf
[Pathway:R-HSA-400511] Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-400540] GIP(52-93) [extracellular region]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:508103] Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
[LiteratureReference:400541] Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
maxDepth
1
modified
[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name
DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)
orthologousEvent
[Reaction:R-GGA-9023626] DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) - Gallus gallus
[Reaction:R-DRE-9023626] DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) - Danio rerio
[Reaction:R-BTA-9023626] DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) - Bos taurus
[Reaction:R-CFA-9023626] DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) - Canis familiaris
[Reaction:R-RNO-9023626] DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) - Rattus norvegicus
[Reaction:R-MMU-9023626] DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) - Mus musculus
output
[EntityWithAccessionedSequence:R-HSA-400542] GIP(54-93) [extracellular region]
precedingEvent
[BlackBoxEvent:R-HSA-400509] Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells - Homo sapiens
releaseDate
2010-09-21
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:879883] Bloom, SR, 2010-06-24
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-9023626
summation
[Summation:400544] Dipeptidyl Peptidase IV (DPP4) cleaves 2 amino acids from th...
Referrals
(replacementInstances)
[Deleted:9023668] Deletion of instance: 400513
(hasEvent)
[Pathway:R-HSA-400511] Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
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