Reactome | CHD1 translation is negatively regulated by miR-26A and B

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9012188] Rothfels, Karen, 2017-07-11
dbId	9012186
displayName	CHD1 translation is negatively regulated by miR-26A and B
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
eventOf	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9012181] CHD1 mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9012130] Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CHD1 translation is negatively regulated by miR-26A and B
output	[EntityWithAccessionedSequence:R-HSA-9012174] CHD1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9011958] miR-26A and B bind to the 3'UTR of the GREB1 mRNA - Homo sapiens [BlackBoxEvent:R-HSA-9011950] Estrogen-responsive GREB1 gene transcription - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:R-HSA-9012221] Negative gene expression regulation by 'CHD1 mRNA:mIR-26 RISC [cytosol]'
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9012186
summation	[Summation:9012187] Translation of CHD1 is negatively regulated by binding of mI...

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