Reactome | CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene

Schema > Reaction > Entries

CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene Show undefined attributes

authored	[InstanceEdit:9009527] Shamovsky, Veronica, 2017-06-20
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9009527] Shamovsky, Veronica, 2017-06-20
dbId	9009526
displayName	CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
eventOf	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression - Homo sapiens
followingEvent	[Reaction:R-HSA-9023860] Histone acetyltransferases are recruited to the TFF1 gene - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-400139] CARM1 [nucleoplasm] [Complex:R-HSA-9009538] TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9009530] Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter [LiteratureReference:9023513] Synergistic, p160 coactivator-dependent enhancement of estrogen receptor function by CARM1 and p300 [LiteratureReference:9023498] Crosstalk between CARM1 methylation and CBP acetylation on histone H3 [LiteratureReference:9023496] Acetylation and methylation in nuclear receptor gene activation
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene
orthologousEvent	[Reaction:R-DME-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Drosophila melanogaster [Reaction:R-DRE-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Danio rerio [Reaction:R-SSC-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Sus scrofa [Reaction:R-BTA-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Bos taurus [Reaction:R-CFA-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Canis familiaris [Reaction:R-RNO-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Rattus norvegicus [Reaction:R-MMU-9009526] CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene - Mus musculus
output	[Complex:R-HSA-9009534] CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm]
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9009526
summation	[Summation:9023783] CARM1 is an H3 R17 methyltransferase that is recruited to th...

Referrals

(hasEvent)	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression
(precedingEvent)	[Reaction:R-HSA-9023860] Histone acetyltransferases are recruited to the TFF1 gene