Reactome | ESR1 binds to TGFA gene promoter

Schema > Reaction > Entries

ESR1 binds to TGFA gene promoter Show undefined attributes

authored	[InstanceEdit:9009527] Shamovsky, Veronica, 2017-06-20
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9008276] Shamovsky, Veronica, 2017-06-08
dbId	9008267
displayName	ESR1 binds to TGFA gene promoter
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
eventOf	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression - Homo sapiens
followingEvent	[Reaction:R-HSA-9008258] NCOA3 binds ESR1:estrogen:TFGA gene - Homo sapiens [Reaction:R-HSA-9008271] CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter - Homo sapiens [Reaction:R-HSA-9008270] NCOA1 binds ESR1:estrogen:TGFA gene - Homo sapiens
input	[Complex:R-HSA-9008284] ESR1 dimer:estrogen [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8864987] TGFA Gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9023519] Transcriptional activation of transforming growth factor alpha by estradiol: requirement for both a GC-rich site and an estrogen response element half-site [LiteratureReference:9008245] Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein [LiteratureReference:9008273] Estrogen receptor interaction with estrogen response elements
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ESR1 binds to TGFA gene promoter
output	[Complex:R-HSA-9008287] ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm]
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9008267
summation	[Summation:9008259] Hormone-activated estrogen receptor (ER) binds with high aff...

Referrals

(precedingEvent)	[Reaction:R-HSA-9008258] NCOA3 binds ESR1:estrogen:TFGA gene [Reaction:R-HSA-9008271] CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter [Reaction:R-HSA-9008270] NCOA1 binds ESR1:estrogen:TGFA gene
(hasEvent)	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression