Reactome | E2F6 binds RBBP8 gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:9007684] Orlic-Milacic, Marija, 2017-05-31
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9007617] Orlic-Milacic, Marija, 2017-05-31
dbId	9007615
displayName	E2F6 binds RBBP8 gene promoter
edited	[InstanceEdit:9007684] Orlic-Milacic, Marija, 2017-05-31
eventOf	[Pathway:R-HSA-8953750] Transcriptional Regulation by E2F6 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9007625] RBBP8 gene expression is inhibited by E2F6 - Homo sapiens
input	[CandidateSet:R-HSA-9007225] E2F6:(TFDP1,TFDP2) [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9007618] RBBP8 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9007077] E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E2F6 binds RBBP8 gene promoter
output	[Complex:R-HSA-9007616] E2F6:(TFDP1.TFDP2):RBBP8 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8953111] E2F6 binds TFDP1 - Homo sapiens [Reaction:R-HSA-8954056] E2F6 binds TFDP2 - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005633] Herlihy, Anna, 2017-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9007615
summation	[Summation:9007619] E2F6, presumably in complex with at least TFDP1 (DP-1) or TF...

(hasEvent)	[Pathway:R-HSA-8953750] Transcriptional Regulation by E2F6
(precedingEvent)	[BlackBoxEvent:R-HSA-9007625] RBBP8 gene expression is inhibited by E2F6

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