Reactome | PVALB gene expression is repressed by MECP2

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9024208] Orlic-Milacic, Marija, 2017-10-02
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9006509] Orlic-Milacic, Marija, 2017-05-16
dbId	9006508
displayName	PVALB gene expression is repressed by MECP2
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
eventOf	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2 - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9006511] Pvalb gene expression is repressed by Mecp2 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9006518] PVALB gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PVALB gene expression is repressed by MECP2
output	[EntityWithAccessionedSequence:R-HSA-9006534] PVALB [cytosol]
precedingEvent	[Reaction:R-HSA-9006503] MECP2 binds the PVALB gene promoter - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:9006532] Negative gene expression regulation by 'MECP2:PVALB gene [nucleoplasm]'
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07 [InstanceEdit:9608114] Christodoulou, John, 2018-08-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9006508
summation	[Summation:9006571] Based on studies in mice, binding of MECP2 to the promoter o...

(hasEvent)	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2
(inferredTo)	[BlackBoxEvent:R-MMU-9006511] Pvalb gene expression is repressed by Mecp2

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