PVALB gene expression is repressed by MECP2

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R-HSA-9006508
Type
Reaction [omitted]
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Homo sapiens
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Based on studies in mice, binding of MECP2 to the promoter of the PVALB gene represses PVALB transcription. Pvalb levels are increased in visual cortical neurons of Mecp2 knockout mice, which is thought to contribute to visual regression (Durand et al. 2012).

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