Reactome | p-Y701-STAT1 dimerizes

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p-Y701-STAT1 dimerizes Show undefined attributes

authored	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
dbId	8985943
displayName	p-Y701-STAT1 dimerizes
edited	[InstanceEdit:9607062] Jassal, Bijay, 2018-04-27
eventOf	[Pathway:R-HSA-8985947] Interleukin-9 signaling - Homo sapiens [Pathway:R-HSA-9860927] Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8985983] p-Y701-STAT1 dimer translocates from the cytosol to the nucleus - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-HSA-8951202] p-Y701-STAT1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8985999] Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis [LiteratureReference:873888] Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	p-Y701-STAT1 dimerizes
orthologousEvent	[Reaction:R-DDI-8985943] p-Y701-STAT1 dimerizes - Dictyostelium discoideum [Reaction:R-CEL-8985943] p-Y701-STAT1 dimerizes - Caenorhabditis elegans [Reaction:R-DME-8985943] p-Y701-STAT1 dimerizes - Drosophila melanogaster [Reaction:R-GGA-8985943] p-Y701-STAT1 dimerizes - Gallus gallus [Reaction:R-XTR-8985943] p-Y701-STAT1 dimerizes - Xenopus tropicalis [Reaction:R-DRE-8985943] p-Y701-STAT1 dimerizes - Danio rerio [Reaction:R-SSC-8985943] p-Y701-STAT1 dimerizes - Sus scrofa [Reaction:R-BTA-8985943] p-Y701-STAT1 dimerizes - Bos taurus [Reaction:R-CFA-8985943] p-Y701-STAT1 dimerizes - Canis familiaris [Reaction:R-RNO-8985943] p-Y701-STAT1 dimerizes - Rattus norvegicus [Reaction:R-MMU-8985943] p-Y701-STAT1 dimerizes - Mus musculus
output	[Complex:R-HSA-8985970] p-Y-STAT1 dimer [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-8985900] p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 - Homo sapiens [BlackBoxEvent:R-HSA-9865511] Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE - Homo sapiens
releaseDate	2018-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28 [InstanceEdit:9607063] Limon, Paula, 2018-04-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8985943
summation	[Summation:8985995] Phosphorylated Signal transducer and activator of transcript...
updateTrackers	[UpdateTracker:9911045] Update Tracker - [Reaction:8985943] p-Y701-STAT1 dimerizes - v89:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9911045] Update Tracker - [Reaction:8985943] p-Y701-STAT1 dimerizes - v89:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-9860927] Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells [Pathway:R-HSA-8985947] Interleukin-9 signaling
(precedingEvent)	[BlackBoxEvent:R-HSA-8985983] p-Y701-STAT1 dimer translocates from the cytosol to the nucleus

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