Reactome | IL15 binds IL2RB:JAK1 and IL2RG:JAK3

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IL15 binds IL2RB:JAK1 and IL2RG:JAK3 Show undefined attributes

authored	[InstanceEdit:9014992] Duenas, Corina, 2017-08-07
category	uncertain
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8983295] Duenas, Corina, 2017-03-23
dbId	8983298
displayName	IL15 binds IL2RB:JAK1 and IL2RG:JAK3
edited	[InstanceEdit:9015191] Duenas, Corina, 2017-08-09
eventOf	[Pathway:R-HSA-8983432] Interleukin-15 signaling - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-447242] IL15 [extracellular region] [Complex:R-HSA-451905] IL2RB:JAK1 [plasma membrane] [Complex:R-HSA-451911] IL2RG:JAK3 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:539064] Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15
maxDepth	1
modified	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
name	IL15 binds IL2RB:JAK1 and IL2RG:JAK3 IL2RB and IL2RG dimerize after IL15 binding IL2RB:JAK1 and IL2RG:JAK3 dimerize after IL15 binding
orthologousEvent	[BlackBoxEvent:R-SSC-8983298] IL15 binds IL2RB:JAK1 and IL2RG:JAK3 - Sus scrofa [BlackBoxEvent:R-BTA-8983298] IL15 binds IL2RB:JAK1 and IL2RG:JAK3 - Bos taurus [BlackBoxEvent:R-MMU-8983298] IL15 binds IL2RB:JAK1 and IL2RG:JAK3 - Mus musculus
output	[Complex:R-HSA-8983134] IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane]
precedingEvent	[Reaction:R-HSA-451900] IL2RB binds JAK1 - Homo sapiens [Reaction:R-HSA-451895] IL2RG binds JAK3 - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-8983298
summation	[Summation:9014990] The Interleukin-15 (IL15) / Interleukin-15 receptor subunit ...

Referrals

(hasEvent)

[Pathway:R-HSA-8983432] Interleukin-15 signaling

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