Reactome | G alpha (q) in G (q):RGS complex is inactivated

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G alpha (q) in G (q):RGS complex is inactivated Show undefined attributes

authored	[InstanceEdit:9014287] Varusai, Thawfeek, 2017-07-27
catalystActivity	[CatalystActivity:8982010] GTPase activity of G alpha (q):GTP:RGS [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:8982022] Varusai, Thawfeek, 2017-03-15
dbId	8982025
displayName	G alpha (q) in G (q):RGS complex is inactivated
edited	[InstanceEdit:9014287] Varusai, Thawfeek, 2017-07-27
eventOf	[Pathway:R-HSA-416476] G alpha (q) signalling events - Homo sapiens
followingEvent	[Reaction:R-HSA-8982026] G alpha (q):RGS dissociates to inactive G alpha (q) - Homo sapiens
input	[Complex:R-HSA-8982027] G alpha (q):GTP:RGS [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8949498] Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits [LiteratureReference:8982372] Regulators of G-protein signalling as new central nervous system drug targets
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	G alpha (q) in G (q):RGS complex is inactivated
orthologousEvent	[Reaction:R-DDI-8982025] G alpha (q) in G (q):RGS complex is inactivated - Dictyostelium discoideum [Reaction:R-CEL-8982025] G alpha (q) in G (q):RGS complex is inactivated - Caenorhabditis elegans [Reaction:R-DME-8982025] G alpha (q) in G (q):RGS complex is inactivated - Drosophila melanogaster [Reaction:R-GGA-8982025] G alpha (q) in G (q):RGS complex is inactivated - Gallus gallus [Reaction:R-XTR-8982025] G alpha (q) in G (q):RGS complex is inactivated - Xenopus tropicalis [Reaction:R-DRE-8982025] G alpha (q) in G (q):RGS complex is inactivated - Danio rerio [Reaction:R-SSC-8982025] G alpha (q) in G (q):RGS complex is inactivated - Sus scrofa [Reaction:R-BTA-8982025] G alpha (q) in G (q):RGS complex is inactivated - Bos taurus [Reaction:R-CFA-8982025] G alpha (q) in G (q):RGS complex is inactivated - Canis familiaris [Reaction:R-RNO-8982025] G alpha (q) in G (q):RGS complex is inactivated - Rattus norvegicus [Reaction:R-MMU-8982025] G alpha (q) in G (q):RGS complex is inactivated - Mus musculus
output	[Complex:R-HSA-8982013] G alpha (q):GDP:RGS [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-HSA-8982017] Active G alpha (q) binds RGS proteins - Homo sapiens
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9618033] Siderovski, David, 2018-09-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8982025
summation	[Summation:8982292] G Protein Coupled Receptors (GPCR) sense extracellular signa...

Referrals

(precedingEvent)	[Reaction:R-HSA-8982026] G alpha (q):RGS dissociates to inactive G alpha (q)
(hasEvent)	[Pathway:R-HSA-416476] G alpha (q) signalling events