Reactome | The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter

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The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter Show undefined attributes

authored	[InstanceEdit:1363332] Orlic-Milacic, Marija, 2011-06-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8964566] Orlic-Milacic, Marija, 2017-02-17
dbId	8964567
displayName	The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter
edited	[InstanceEdit:8961898] Orlic-Milacic, Marija, 2017-02-06
eventOf	[Pathway:R-HSA-1362300] Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8961934] CDK1 gene expression is stimulated by E2F1 and repressed by RBL1 and RBL2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-8978980] The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds Cdk1 gene promoter - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-8961921] CDK1 gene [nucleoplasm] [DefinedSet:R-HSA-8964549] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1362298] E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter
output	[Complex:R-HSA-8964568] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CDK1 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-1227671] Recruitment of HDAC1 by p107 (RBL1) - Homo sapiens [Reaction:R-HSA-1227670] Recruitment of HDAC1 by p130 (RBL2) - Homo sapiens
releaseDate	2011-09-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1538129] MacPherson, D, 2011-08-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8964567
summation	[Summation:8964569] In G0 and early G1, complexes containing p130 (RBL2) and p10...

Referrals

(hasEvent)	[Pathway:R-HSA-1362300] Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
(precedingEvent)	[BlackBoxEvent:R-HSA-8961934] CDK1 gene expression is stimulated by E2F1 and repressed by RBL1 and RBL2
(inferredTo)	[Reaction:R-MMU-8978980] The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds Cdk1 gene promoter

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