Reactome | Recruitment of HDAC1 by p107 (RBL1)

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Recruitment of HDAC1 by p107 (RBL1) Show undefined attributes

authored	[InstanceEdit:1363332] Orlic-Milacic, Marija, 2011-06-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1227672] Orlic-Milacic, Marija, 2011-03-09
dbId	1227671
displayName	Recruitment of HDAC1 by p107 (RBL1)
eventOf	[Pathway:R-HSA-1538133] G0 and Early G1 - Homo sapiens
followingEvent	[Reaction:R-HSA-8964561] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds MYBL2 gene promoter - Homo sapiens [Reaction:R-HSA-8964567] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter - Homo sapiens [Reaction:R-HSA-8964580] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter - Homo sapiens [Reaction:R-HSA-8964550] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds E2F1 gene promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-205021] HDAC1 [nucleoplasm] [Complex:R-HSA-1226088] RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1227660] The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase
modified	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
name	Recruitment of HDAC1 by p107 (RBL1) HDAC1 + p107(RBL1):E2F4:DP1 => HDAC1-p107(RBL2):E2F4:DP1
orthologousEvent	[Reaction:R-DDI-1227671] Recruitment of HDAC1 by p107 (RBL1) - Dictyostelium discoideum [Reaction:R-CEL-1227671] Recruitment of HDAC1 by p107 (RBL1) - Caenorhabditis elegans [Reaction:R-DME-1227671] Recruitment of HDAC1 by p107 (RBL1) - Drosophila melanogaster [Reaction:R-GGA-1227671] Recruitment of HDAC1 by p107 (RBL1) - Gallus gallus [Reaction:R-XTR-1227671] Recruitment of HDAC1 by p107 (RBL1) - Xenopus tropicalis [Reaction:R-SSC-1227671] Recruitment of HDAC1 by p107 (RBL1) - Sus scrofa [Reaction:R-BTA-1227671] Recruitment of HDAC1 by p107 (RBL1) - Bos taurus [Reaction:R-CFA-1227671] Recruitment of HDAC1 by p107 (RBL1) - Canis familiaris [Reaction:R-RNO-1227671] Recruitment of HDAC1 by p107 (RBL1) - Rattus norvegicus [Reaction:R-MMU-1227671] Recruitment of HDAC1 by p107 (RBL1) - Mus musculus
output	[Complex:R-HSA-1227668] HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
releaseDate	2011-09-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1538129] MacPherson, D, 2011-08-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1227671
summation	[Summation:1362280] p107 (RBL1) in complex with E2F4 and DP1 or DP2 recruits his...

Referrals

(precedingEvent)

[Reaction:R-HSA-8964561] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds MYBL2 gene promoter
[Reaction:R-HSA-8964567] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter
[Reaction:R-HSA-8964580] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter
[Reaction:R-HSA-8964550] The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds E2F1 gene promoter

(hasEvent)

[Pathway:R-HSA-1538133] G0 and Early G1

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