Reactome | ADPRHL2 hydrolyses poly(ADP-ribose)

Schema > Depolymerisation > Entries

ADPRHL2 hydrolyses poly(ADP-ribose) Show undefined attributes

authored	[InstanceEdit:8952907] Jassal, Bijay, 2016-12-20
catalystActivity	[CatalystActivity:8952897] poly(ADP-ribose) glycohydrolase activity of ADPRHL2 [mitochondrial matrix]
category	dissociation
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:8952907] Jassal, Bijay, 2016-12-20
dbId	8952903
displayName	ADPRHL2 hydrolyses poly(ADP-ribose)
edited	[InstanceEdit:8952907] Jassal, Bijay, 2016-12-20
eventOf	[Pathway:R-HSA-110362] POLB-Dependent Long Patch Base Excision Repair - Homo sapiens
input	[SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [Polymer:R-ALL-8952909] poly(ADP-ribose) [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8952901] Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase [LiteratureReference:8952911] ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose) glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose) [LiteratureReference:8952898] Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	ADPRHL2 hydrolyses poly(ADP-ribose)
orthologousEvent	[Depolymerisation:R-GGA-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Gallus gallus [Depolymerisation:R-XTR-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Xenopus tropicalis [Depolymerisation:R-DRE-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Danio rerio [Depolymerisation:R-SSC-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Sus scrofa [Depolymerisation:R-BTA-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Bos taurus [Depolymerisation:R-RNO-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Rattus norvegicus [Depolymerisation:R-MMU-8952903] ADPRHL2 hydrolyses poly(ADP-ribose) - Mus musculus
output	[SimpleEntity:R-ALL-8952905] ADP-ribose [mitochondrial matrix] [Polymer:R-ALL-8952909] poly(ADP-ribose) [mitochondrial matrix]
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8954302] D'Eustachio, Peter, 2017-01-06
schemaClass	Depolymerisation
species	[Species:48887] Homo sapiens
stId	R-HSA-8952903
summation	[Summation:8952899] Important cellular processes such as DNA repair, cellular di...

Referrals

(hasEvent)

[Pathway:R-HSA-110362] POLB-Dependent Long Patch Base Excision Repair