Reactome | TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane

Schema > Reaction > Entries

TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane Show undefined attributes

authored	[InstanceEdit:8951874] Jassal, Bijay, 2016-12-12
catalystActivity	[CatalystActivity:8951851] cholesterol transfer activity of TSPO:BZRAP1 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:8951874] Jassal, Bijay, 2016-12-12
crossReference	[DatabaseIdentifier:12668109] RHEA:39747
dbId	8951850
displayName	TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane
edited	[InstanceEdit:8951874] Jassal, Bijay, 2016-12-12
eventOf	[Pathway:R-HSA-196108] Pregnenolone biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-193054] Oxidation of cholesterol to 22beta-hydroxycholesterol - Homo sapiens
input	[SimpleEntity:R-ALL-8951853] CHOL [mitochondrial outer membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8951858] Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor [LiteratureReference:8951875] The human peripheral benzodiazepine receptor gene: cloning and characterization of alternative splicing in normal tissues and in a patient with congenital lipoid adrenal hyperplasia [LiteratureReference:8951847] Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis [LiteratureReference:8951867] The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane [LiteratureReference:8951873] Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane
orthologousEvent	[Reaction:R-CEL-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Caenorhabditis elegans [Reaction:R-DME-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Drosophila melanogaster [Reaction:R-GGA-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Gallus gallus [Reaction:R-SSC-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Sus scrofa [Reaction:R-CFA-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Canis familiaris [Reaction:R-RNO-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Rattus norvegicus [Reaction:R-MMU-8951850] TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane - Mus musculus
output	[SimpleEntity:R-ALL-193156] CHOL [mitochondrial inner membrane]
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8954302] D'Eustachio, Peter, 2017-01-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8951850
summation	[Summation:8951849] The 18 kDa translocator protein (TSPO), originally identifie...

Referrals

(hasEvent)	[Pathway:R-HSA-196108] Pregnenolone biosynthesis
(precedingEvent)	[Reaction:R-HSA-193054] Oxidation of cholesterol to 22beta-hydroxycholesterol