Reactome | TEADs:YAP1 binds CTGF gene

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TEADs:YAP1 binds CTGF gene Show undefined attributes

authored	[InstanceEdit:8951943] Orlic-Milacic, Marija, 2016-12-12
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8951696] Orlic-Milacic, Marija, 2016-12-08
dbId	8951695
displayName	TEADs:YAP1 binds CTGF gene
edited	[InstanceEdit:8959863] Orlic-Milacic, Marija, 2017-01-31
eventOf	[Pathway:R-HSA-8951671] RUNX3 regulates YAP1-mediated transcription - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-1989766] Expression of CTGF - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5649937] CTGF gene [nucleoplasm] [DefinedSet:R-HSA-8869639] TEADs:YAP1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8951887] TEAD mediates YAP-dependent gene induction and growth control [LiteratureReference:8951545] RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TEADs:YAP1 binds CTGF gene
output	[Complex:R-HSA-8951697] TEADs:YAP1:CTGF gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8951676] RUNX3 binds TEADs and YAP1 - Homo sapiens
regulatedBy	[NegativeRegulation:R-HSA-8951699] Negative regulation by 'RUNX3:YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm]'
regulationReference	[RegulationReference:9642404] Negative regulation by 'RUNX3:YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm]' RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8959885] Ito, Yoshiaki, 2017-01-31 [InstanceEdit:8959883] Chuang, Linda Shyue Huey, 2017-01-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8951695
summation	[Summation:8951889] The complex of YAP1 and one TEAD proteins (TEAD1, TEAD2, TEA...

Referrals

(hasEvent)	[Pathway:R-HSA-8951671] RUNX3 regulates YAP1-mediated transcription
(precedingEvent)	[BlackBoxEvent:R-HSA-1989766] Expression of CTGF

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