Reactome | Negative regulation by 'RUNX3:CTNNB1:TCF7L2,(LEF1) [nucleoplasm]'

Schema > NegativeRegulation > Entries

activeUnit	[Complex:R-HSA-8865463] RUNX3:CBFB [nucleoplasm] - Homo sapiens
created	[InstanceEdit:8951510] Orlic-Milacic, Marija, 2016-12-07
dbId	8951513
displayName	Negative regulation by 'RUNX3:CTNNB1:TCF7L2,(LEF1) [nucleoplasm]'
modified	[InstanceEdit:9608020] Wu, G, 2018-05-08
regulatedEntity	[Reaction:R-HSA-8951442] CTNNB1:TCF7L2,LEF1 binds the CCND1 gene promoter - Homo sapiens
regulator	[Complex:R-HSA-8951514] RUNX3:CTNNB1:TCF7L2,(LEF1) [nucleoplasm]
schemaClass	NegativeRegulation
stId	R-HSA-8951513

(regulation)	[RegulationReference:9641299] Negative regulation by 'RUNX3:CTNNB1:TCF7L2,(LEF1) [nucleoplasm]' RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis
(regulatedBy)	[Reaction:R-HSA-8951442] CTNNB1:TCF7L2,LEF1 binds the CCND1 gene promoter

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