Reactome | Negative regulation by 'IL12B [extracellular region]'

Schema > NegativeRegulation > Entries

created	[InstanceEdit:8951162] Duenas, Corina, 2016-12-02
dbId	8951201
displayName	Negative regulation by 'IL12B [extracellular region]'
modified	[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
regulatedEntity	[Reaction:R-HSA-447226] Interleukin-12 binds Interleukin-12 receptor - Homo sapiens
regulator	[EntityWithAccessionedSequence:R-HSA-447181] IL12B [extracellular region]
schemaClass	NegativeRegulation
stId	R-HSA-8951201

(regulation)	[RegulationReference:9642270] Negative regulation by 'IL12B [extracellular region]' Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
(regulatedBy)	[Reaction:R-HSA-447226] Interleukin-12 binds Interleukin-12 receptor

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