Reactome | p-Y693-STAT4 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

p-Y693-STAT4 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-8952795] 2xp-Y693-STAT4:IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] - Homo sapiens [Complex:R-HSA-8952795] 2xp-Y693-STAT4:IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] - Homo sapiens [Complex:R-HSA-8952748] IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:p-Y705-STAT3:p-Y693-STAT4 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8950778] p-Y693-STAT4 dimerizes - Homo sapiens [Reaction:R-HSA-8950778] p-Y693-STAT4 dimerizes - Homo sapiens [Reaction:R-HSA-8950780] p-Y705-STAT3 binds p-Y693-STAT4 - Homo sapiens
created	[InstanceEdit:8950688] Duenas, Corina, 2016-12-02
dbId	8950343
displayName	p-Y693-STAT4 [cytosol]
endCoordinate	748
hasModifiedResidue	[ModifiedResidue:8950532] O4'-phospho-L-tyrosine at 693
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-8950343] phospho-Stat4 [cytosol] - Mus musculus [GenomeEncodedEntity:R-RNO-8950343] Ghost homologue of p-Y693-STAT4 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-8950343] phospho-STAT4 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-8950343] phospho-STAT4 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-8950343] phospho-STAT4 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-8950343] phospho-stat4 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-8950343] phospho-stat4 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-8950343] phospho-STAT4 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-8950343] phospho-Stat92E [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-8950343] phospho-p-Y693-STAT4 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-8950343-2] phospho-sta-2 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-8950343-3] phospho-sta-1 [cytosol] - Caenorhabditis elegans [DefinedSet:R-CEL-8950343-4] Homologues of p-Y693-STAT4 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-8950343] phospho-dstA [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-8950343-2] phospho-p-Y693-STAT4 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-8950343-3] phospho-dstC [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-8950343-4] phospho-p-Y693-STAT4 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-8950343-5] phospho-p-Y693-STAT4 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-8950343-6] phospho-dstB [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-8950343-7] phospho-dstD [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-8950343-8] Homologues of p-Y693-STAT4 [cytosol] - Dictyostelium discoideum
literatureReference	[LiteratureReference:8950738] Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling
maxDepth	1
memberOf	[DefinedSet:R-HSA-9006876] p-Y701-STAT1, p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol] - Homo sapiens
name	p-Y693-STAT4 p-STAT4
producedByEvent	[BlackBoxEvent:R-HSA-8952807] p-Y693-STAT4 dissociates after IL12:IL12R interaction - Homo sapiens [BlackBoxEvent:R-HSA-8952807] p-Y693-STAT4 dissociates after IL12:IL12R interaction - Homo sapiens [BlackBoxEvent:R-HSA-8952823] p-Y693-STAT4, p-Y705-STAT3 dissociate from IL23:IL23 receptor - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q14765] UniProt:Q14765 STAT4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8950343
startCoordinate	1

Referrals

(output)	[BlackBoxEvent:R-HSA-8952823] p-Y693-STAT4, p-Y705-STAT3 dissociate from IL23:IL23 receptor [BlackBoxEvent:R-HSA-8952807] p-Y693-STAT4 dissociates after IL12:IL12R interaction
(hasComponent)	[Complex:R-HSA-8952748] IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:p-Y705-STAT3:p-Y693-STAT4 [plasma membrane] [Complex:R-HSA-8950427] p-Y705-STAT3:p-Y693-STAT4 [cytosol] [Complex:R-HSA-8952795] 2xp-Y693-STAT4:IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] [Complex:R-HSA-8950602] p-Y693-STAT4 dimer [cytosol]
(input)	[Reaction:R-HSA-8950780] p-Y705-STAT3 binds p-Y693-STAT4 [Reaction:R-HSA-8950778] p-Y693-STAT4 dimerizes
(hasMember)	[DefinedSet:R-HSA-9006876] p-Y701-STAT1, p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol]

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