Reactome | IL12A:IL12B [endoplasmic reticulum lumen]

Schema > Complex > Entries

IL12A:IL12B [endoplasmic reticulum lumen] Show undefined attributes

compartment	[Compartment:17957] endoplasmic reticulum lumen
consumedByEvent	[BlackBoxEvent:R-HSA-8950575] IL12A:IL12B translocates from ER lumen to Golgi - Homo sapiens
created	[InstanceEdit:8950119] Duenas, Corina, 2016-12-02
dbId	8950122
displayName	IL12A:IL12B [endoplasmic reticulum lumen]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8950139] IL12A [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-HSA-8950126] IL12B [endoplasmic reticulum lumen]
inDisease	false
inferredTo	[Complex:R-MMU-8950122] IL12A:IL12B [endoplasmic reticulum lumen] - Mus musculus [Complex:R-RNO-8950122] IL12A:IL12B [endoplasmic reticulum lumen] - Rattus norvegicus [Complex:R-CFA-8950122] IL12A:IL12B [endoplasmic reticulum lumen] - Canis familiaris [Complex:R-BTA-8950122] IL12A:IL12B [endoplasmic reticulum lumen] - Bos taurus [Complex:R-SSC-8950122] IL12A:IL12B [endoplasmic reticulum lumen] - Sus scrofa [Complex:R-GGA-8950122] IL12A:IL12B [endoplasmic reticulum lumen] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:447201] Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12 [LiteratureReference:8950121] The metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion [LiteratureReference:8950127] Molecular characterization of interleukin 12
maxDepth	2
name	IL12A:IL12B Interleukin-12A:Interleukin-12B
producedByEvent	[BlackBoxEvent:R-HSA-8950113] IL12A binds IL12B - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8950122
summation	[Summation:8950124] The Interleukin-12 heterodimer (IL-12) is formed by Interleu...

Referrals

(output)	[BlackBoxEvent:R-HSA-8950113] IL12A binds IL12B
(input)	[BlackBoxEvent:R-HSA-8950575] IL12A:IL12B translocates from ER lumen to Golgi

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